Identification of transcriptionally induced Z-DNA segments in the human C-MYC gene. Transcription of human C-MYC in permeabilized nuclei is associated with formation of Z-DNA in three discrete regions of the gene. Wittig, B., Wolfl, S., Dorbic, T., Vahrson, W. Transcription is associated with Z-DNA formation in metabolically active permeabilized mammalian cell nuclei. The level of Z-DNA in metabolically active, permeabilized mammalian cell nuclei is regulated by torsional strain. A gentle method for preparing cyto- and nucleo-skeletons and associated chromatin. Mapping Z-DNA in the human genome: computer aided mapping reveals a non-random distribution of potential Z-DNA forming sequences in human genes. Supercoiling of the DNA template during transcription. Antibodies against Z-DNA react with the macronucleus but not the micronucleus of the hypotrichous ciliate Stylonychia mytilus. Left-handed Z-DNA in bands of acid-fixed polytene chromosomes. Z-DNA in transcriptionally active chromosomes. Antibodies to left-handed Z-DNA bind to interband regions of Drosophila polytene chromosomes. Z-DNA specific antibodies in human systemic lupus erythematosus. Monoclonal antibodies recognize different parts of Z-DNA. M., Moller, A., Nordheim, A., Stollar, B. A computer aided thermodynamic approach for predicting the formation of Z-DNA in naturally occurring sequences. Sequence-dependent energetics of the BвЂ“Z transition in supercoiled DNA containing nonalternating purineвЂ“pyrimidine sequences. d(pCpG)n DNA sequences from right to left-handed helical structure by salt, Co(III), or negative supercoiling.Z-DNA forms without an alternating purineвЂ“pyrimidine sequence in solution. Facile transition of poly into a left-handed helix in physiological conditions. (dGвЂ“dT)n forms left-handed Z-DNA in negatively supercoiled plasmids.The chemistry and biology of left-handed Z-DNA. Effects of methylation on a synthetic polynucleotide: the BвЂ“Z transition in poly(dGвЂ“m5dC) poly(dG-dC) is left handed Z-DNA: raman spectra of crystals and solutions.Salt-induced co-operative conformational change of a synthetic DNA: equilibrium and kinetic studies with poly(dG-dC).

Molecular structure of a left-handed double helical DNA fragment at atomic resolution.

A form b form z form dna